New PDF release: Antibacterial Agents: Chemistry, Mode of Action, Mechanisms

By Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

ISBN-10: 0470972440

ISBN-13: 9780470972441

ISBN-10: 0470972459

ISBN-13: 9780470972458

Antibacterial brokers act opposed to bacterial an infection both via killing the bacterium or by means of arresting its progress. They do that by way of concentrating on bacterial DNA and its linked techniques, attacking bacterial metabolic procedures together with protein synthesis, or interfering with bacterial cellphone wall synthesis and function.

Antibacterial Agents is a necessary advisor to this crucial type of chemotherapeutic medicinal drugs. Compounds are organised in line with their goal, which is helping the reader comprehend the mechanism of motion of those medicinal drugs and the way resistance can come up. The e-book makes use of an built-in “lab-to-clinic” strategy which covers drug discovery, resource or synthesis, mode of motion, mechanisms of resistance, medical elements (including hyperlinks to present guidance, major drug interactions, cautions and contraindications), prodrugs and destiny improvements.

Agents lined include:

  • agents focusing on DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents
  • agents focusing on metabolic procedures -  sulfonamide antibacterial brokers and trimethoprim
  • agents focusing on protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones
  • agents concentrating on cellphone wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin

Antibacterial Agents will discover a position at the bookshelves of scholars of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

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Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications by Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

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